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Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidization of fatty acids, and the oxidation of pyruvate in the citric acid cycle. It is adapted from cysteamine, panthothenate and adenosine triphosphate. Its chemical formula is C₂₁H₃₆N₇O₁₆P₃S.

Contents 1 Function 2 List of coenzyme A activated acyl groups 3 References 4 External links

[edit] Function

Since coenzyme A is chemically a thiol, it can react with carboxylic acids to form of thioesters, thus functioning as an acyl group carrier. A molecule of coenzyme A carrying an acetyl group is also referred to as acetyl-CoA. When it is not attached to an acyl group it is usually referred to as 'CoASH' or 'HSCoA'.

[edit] List of coenzyme A activated acyl groups

• Acetyl-CoA
• Acetoacetyl-CoA
• HMG-CoA
• Malonyl-CoA
• Propionyl-CoA
• Succinyl-CoA

[edit] References

• Karl Miller (1998). Beta Oxidation of Fatty Acids. Retrieved May 18, 2005.
• Charles Ophard (2003). Acetyl-CoA Crossroads. Retrieved May 18, 2005.
• Lehninger principles of biochemistry, 4th edition, David L. Nelson, Michael M. Cox

[edit] External links

• Link page to external chemical sources.de:Coenzym A

eo:Acetila Koenzimo A fr:Coenzyme A lb:HSCoA ja:補酵素A pl:Koenzym A pt:Acetil coenzima A se:Koenzym A fi:Asetyylikoentsyymi-A vi:Coenzyme A zh:乙酰辅酶A