Betulin
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| Betulin | |
|---|---|
| Image:Betulin.jpg | |
| General | |
| Systematic name | 3a-Hydroxymethyl-1-isopropenyl -5a,5b,8,8,11a-pentamethyl- icosahydro-cyclopenta[a]chrysen-9-ol |
| Other names | lup-20(29)-ene-3β,28-diol |
| Molecular formula | C30H50O2 |
| Molar mass | 442.72 g/mol |
| CAS number | [473-98-3] |
| Properties | |
| Melting point | 256-257 °C |
| CLogP | 8.526 |
| Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references | |
Betulin (lup-20(29)-ene-3β,28-diol)is an abundant naturally occurring triterpene. It is commonly isolated from the bark of birch trees and forms up to 30% of the dry weight of the extractive. It can be converted to Betulinic acid. Betulinic acid and its synthetic analogues exhibit anti-malarial, anti-inflamatory and anti-HIV activity as well as showing cytotoxicity towards a number of tumour cell lines.
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