The following is a list of the top 50 pharmaceutical and biotech companies ranked by healthcare revenue. Some companies (eg, Bayer) have additional chemicals revenue not included here. The phrase Big Pharma is often used to refer to companies with revenue in excess of $3 billion, and/or R&D expenditure in excess of $500 million, and represents the first 30 or so companies in this list.

Rank 2004	Company	Country	Healthcare Revenue 2004 (USD millions)	Healthcare R&D 2004 (USD millions)	Net Income/ (Loss) 2004 (USD millions)	Employees 2004
1	Pfizer	USA	52,516	7,684	11,361	115,000
2	Johnson & Johnson	USA	47,348	5,203	8,509	109,900
3	GlaxoSmithKline	UK	37,318	5,204	7,886	100,619
4	Sanofi-Aventis	France	31,615	4,927	6,526	96,439
5	Novartis	Switzerland	28,247	4,207	5,767	81,392
6	Hoffmann-La Roche	Switzerland	25,163	4,098	5,344	64,703
7	Merck & Co.	USA	22,939	4,010	5,813	62,600
8	AstraZeneca	UK	21,427	3,803	3,813	64,200
9	Abbott Laboratories	USA	19,680	1,697	3,236	50,600
10	Bristol-Myers Squibb	USA	19,380	2,500	2,388	43,000
11	Wyeth	USA	17,358	2,461	1,234	51,401
12	Eli Lilly and Company	USA	13,858	2,591	1,810	44,500
13	Bayer	Germany	10,554	1,299	750	113,060
14	Amgen	USA	10,550	2,028	2,363	14,400
15	Boehringer Ingelheim	Germany	10,146	1,532	1,104	35,529
16	Baxter International	USA	9,509	517	388	48,000
17	Takeda Pharmaceutical Co.	Japan	9,330	1,285	2,636	14,510
18	Schering-Plough	USA	8,272	1,607	-981	30,500
19	Astellas Pharma	Japan	7,904	1,213	566	15,500
20	Procter & Gamble	USA	7,786	n/a	7,257	110,000
21	Schering	Germany	5,103	1,143	622	26,131
22	Merck KGaA	Germany	5,018	611	836	28,877
23	Eisai Co.	Japan	4,857	744	527	8,295
24	Novo Nordisk	Denmark	4,847	727	837	20,285
25	Teva Pharmaceutical Industries	Israel	4,799	338	332	13,813
26	Genentech	USA	4,621	948	785	7,646
27	Sankyo Co.	Japan	4,329	822	459	11,444
28	Akzo Nobel	The Netherlands	4,037	644	1,065	61,400
29	Alcon	Switzerland	3,914	390	872	12,200
30	Forest Laboratories	USA	3,160	294	839	5,136
31	Daiichi Pharmaceutical Co.	Japan	2,964	546	353	7,333
32	Chugai Pharmaceutical Co.	Japan	2,833	463	328	5,327
33	Taisho Pharmaceutical	Japan	2,655	221	337	5,378
34	Altana	Germany	2,623	506	486	10,783
35	Serono	Switzerland	2,458	595	494	4,902
36	Bausch & Lomb	USA	2,232	163	160	12,400
37	Mitsubishi Pharma	Japan	2,226	480	125	5,917
38	Biogen Idec	USA	2,210	684	518	4,266
39	Genzyme	USA	2,201	392	87	7,100
40	Solvay	Belgium	2,170	366	673	29,300
41	UCB	Belgium	2,088	404	451	11,403
42	Allergan	USA	2,046	346	377	5,030
43	Kyowa Hakko Kogyo Co.	Japan	2,035	230	170	5,960
44	Shionogi & Co.	Japan	1,862	279	180	5,522
45	Ivax	USA	1,837	142	198	10,100
46	Chiron Corporation	USA	1,723	431	79	5,400
47	Watson Pharmaceuticals	USA	1,641	134	151	3,851
48	H. Lundbeck	Denmark	1,625	296	288	5,155
49	Sumitomo Chemical Co.	Japan	1,622	239	612	20,195
50	Tanabe Seiyaku Co.	Japan	1,509	264	151	4,517

Source: Top 50 pharmaceutical companies, MedAdNews, September 2005

[edit] Alphabetical listing

This is an incomplete list, which may never be able to satisfy certain standards for completeness. Revisions and sourced additions are welcome.

[edit] 1-A

3M, a diversified global technology company based in the United States which produces pharmaceuticals as part of its health care business
Abbott Laboratories, a top-20 pharma company based in the United States
Able Laboratories (external link), a former American generic pharmaceutical manufacturer which entered bankruptcy in 2005
Aburaihan (external link), the largest Iranian pharmaceutical manufacturer
Alkermes, an American company
Allergan, an American multinational
Almirall Prodesfarma, a Spanish multinational
Alphapharm, an Australian generic pharmaceutical manufacturer and a wholly owned subsidiary of Merck KGaA
Altana Pharma AG, formerly Byk Gulden, part of Altana AG, a German maker of chemicals and pharmaceuticals
Amico Laboratories, a pharma company based in Bangladesh
ALZA Corporation, an American company acquired by Johnson & Johnson in 2001
Amgen, a top-20 pharma company based in the United States
Antara Biosciences, a biotechnology company based in the United States
Astellas Pharma, a Japanese company formed in 2005 through the merger of Fujisawa Pharmaceutical and Yamanouchi Pharmaceutical
Astra AB, a former Swedish company which in 1999 merged with Zeneca Group PLC to form AstraZeneca
AstraZeneca, a top-20 pharma company based in the United Kingdom formed in 1999 through the merger of Astra AB and Zeneca Group PLC
Aventis, a former French company which in 2004 merged with Sanofi-Synthélabo to form Sanofi-Aventis
Axcan Pharma, a specialty pharma company based in Quebec, Canada

[edit] B-D

Bakhtar Bioshimi (external link), an Iranian generic pharmaceutical manufacturer
BARGN FARMACEUTICI, a pharmaceutical distributor based in the Philippines
Barr, a specialty pharma company based in the United States
Bayer, a top-20 pharma company based in Germany
Beximco Pharmaceuticals Ltd, pharma company based in Bangladesh
Biogen Idec, an American company formed in 2003 through the merger of Biogen and Idec Pharmaceuticals
Biolex, an American company
BioPort, an American vaccine manufacturer and a subsidiary of Emergent BioSolutions
Biotecnol, a Portuguese company
Biovail, the largest Canadian pharmaceutical company
Biovitrum, a Swedish company
Boehringer-Ingelheim, a top-20 pharma company based in Germany
Bristol-Myers Squibb, a top-20 pharma company based in the United States
Catalytica, a former American company which merged with Synotex Company in 2000 to form DSM Catalytica Pharmaceuticals, now known as DSM Pharmaceuticals
CCL Pharmaceuticals (external link), a Pakistani company
Celltech, a former British company acquired by the Belgian company UCB in 2004
Century Pharmaceuticals (external link), an Indian company
Cephalon (external link), an American company known for the narcolepsy drug, Modafinil
Cilag, a Swiss subsidiary of Johnson & Johnson
Cipla, an Indian company best known as a manufacturer of anti-AIDS drugs
Claris Lifesciences (external link), a multinational based in India
Daiichi Pharmaceuticals, a former Japanese company which merged with Sankyo Co., Ltd. in 2005 to form Daiichi Sankyo
Daiichi Sankyo, a Japanese holding company established in 2005 for the management integration of Sankyo and Daiichi Pharmaceuticals
Diosynth, a former Dutch company acquired in 2005 by the American firm Organon International, which is in turn a part of the Dutch Akzo Nobel
Douglas Pharmaceuticals (external link), a New Zealand-based company
Dow Pharmaceutical Sciences (external link), an American company focused on topical therapeutics
DSM Pharmaceuticals

•Chiesi Pharmaceutical an Italian company having a dymnamic R&D department. Subsidiaries in many countries of the world including Pakistan.

[edit] E-L

Eli Lilly and Company, a top-20 pharma company based in the United States
Ethypharm (external link) a French company specialized in the development of drug delivery solutions for the pharmaceutical industry
Ferozsons Laboratories, A Pakistani based company which is exclusively focused on Gastroenterology.
Galderma, A French based company which is exclusively focused on Dermatology
Genentech, an American biopharmaceutical company, considered to have founded the biotechnology industry as a whole
Genzyme, an American company
Gilead Sciences, an American biopharmaceutical company
GlaxoSmithKline, a top-20 pharma company based in the United Kingdom
GPC Biotech, a German biopharmaceutical company
Grindex external link, the largest pharmaceutical company in the Baltic States.
Hexal Australia, an Australian generic pharmaceutical manufacturer, part of the Hexal International Group
Hexal International Group (external link), a German generic pharmaceutical manufacturer
Hoffmann-La Roche, or Roche, a top-20 pharma company based in Switzerland
ICN Pharmaceuticals, now known as Valeant
Institute for OneWorld Health, a nonprofit American pharmaceutical company focused on developing infectious disease drugs for developing countries
Ipsen (external link), a French company
Isis Pharmaceuticals (external link), an American company focused on development of RNA-based therapeutics
Janssen Pharmaceutica Products, a subsidiary of Johnson & Johnson
Janssen-Cilag, a subsidiary of Johnson & Johnson
Jelfa SA (external link), a Polish generic pharmaceutical manufacturer
Johnson & Johnson, a top-20 pharma company based in the United States
King Pharmaceuticals, an American company
Knoll Pharmaceuticals, formerly the pharmaceutical division of BASF, acquired by Abbott in 2001
Krka, d. d., a Slovenian generic pharmaceutical and cosmetics manufacturer
Kurve Technology, Inc. (external link) an American company specialized in the development of drug delivery solutions for the pharmaceutical industry
LEO Pharma, a Danish pharmaceutical company
Lundbeck, a Danish company

[edit] M-Z

Mansfield-King
MedImmune
Menarini (external link)
Merck & Co.
Merck KGaA
Merix Pharmaceutical Corp. (Merix Health Care Products) Based in USA
Meyer Organics
Millennium Pharmaceuticals
Napp Pharmaceuticals (external link)
Novartis
Novo Nordisk
Nucleics DNA sequencing reagents, services & software
Ordain Health Care [1]
Organon International (Organon) products, the healthcare division of Akzo Nobel
Ortho-McNeil Pharmaceutical
Otsuka Pharmaceutical Co. (external link), based in Japan
Ovation Pharma
Pfizer
Pharmacia, now part of Pfizer
Pharmacosmos, a pharmaceutical company based in Denmark
Pierre Fabre Group
Pliva
Procter & Gamble
Purdue Pharma, private company, maker of Oxcycontin
Ranbaxy
Renovo, plc (external link), world leader in scar prevention and reduction research
Roche
Searle Pharmaceutical, A leading Pharmaceutical of Pakistan
Sanofi-Aventis, a global top-20 pharma company based in France
Schering, a German company
Schering-Plough, an American company created during World War II through seizure of assets from Schering
Serono, a Swiss biopharmaceutical company
Servier Laboratories
Shire Pharmaceuticals Group, a British company
Sigma-Tau (external link)
Solvay Group
Sugen, purchased by Pfizer in 2003
Square Pharmaceuticals Ltd. Bangladesh
Takeda, a top-20 pharma company based in Japan
TAP Pharmaceutical Products, Inc (external link), a joint-venture of Abbott and Takeda, created without discovery or manufacturing capabilities
Teva Pharmaceutical Industries, (external link) a global (top-20) manufacturer of mainly generic pharmaceuticals, based in Israel.
UCB, a Belgian biopharmaceutical company
Upsher-Smith Laboratories (external link), a branded generic manufacturer
Valeant, formerly ICN Pharmaceuticals, an American company
Vertex Pharmaceuticals, an American company
Vion Pharmaceuticals, Inc., an American company
ViroPharma, an American company
Wyeth, formerly American Home Products, a top-20 pharma company based in the United States
Xencor (external link), a biopharmaceutical company without marketed products as of April 2006