C4BPA (protein)
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| complement component 4 binding protein, alpha
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| Identifiers | |
| Symbol(s) | C4BPA C4BP |
| Entrez | 722 |
| OMIM | 120830 |
| RefSeq | NM_000715 |
| UniProt | P04003 |
| Other data | |
| Locus | Chr. 1 q32 |
C4BPB is a protein involved in the complement system. It inhibits the action of C4. C4BP has a hydra-like structure with a central stalk and seven branching alpha-chains. It splits C4 convertase and is a cofactor for factor I which cleaves C4b. C4BP binds necrotic cells and DNA, to clean up after inflammation. It also binds CD40 on B cells which potentiaties proliferation and costimulation.
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| Complement system - edit |
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Activators:
C6 |
C7 |
C9 |
MBL2 |
PFC
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