Choline acetyltransferase
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| choline acetyltransferase
| |
| Identifiers | |
| Symbol(s) | CHAT |
| Entrez | 1103 |
| OMIM | 118490 |
| RefSeq | NM_020549 |
| UniProt | P28329 |
| Other data | |
| EC number | 2.3.1.6 |
| Locus | Chr. 10 q11.2 |
Choline acetyltransferase (EC 2.3.1.6) is an enzyme which is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. It joins Acetyl CoA to choline, resulting in the formation of the neurotransmitter acetylcholine. It is often used as a marker, immunohistochemically, for motor neurons (motoneurons).
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