Ciclopirox
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| Image:Ciclopirox.svg | |
| Ciclopirox
| |
| Systematic (IUPAC) name | |
| 6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one | |
| Identifiers | |
| CAS number | 29342-05-0 |
| ATC code | D01AE14 G01AX12 |
| PubChem | 2749 |
| DrugBank | APRD00871 |
| Chemical data | |
| Formula | C12H17NO2 |
| Mol. weight | 207.269 g/mol |
| Pharmacokinetic data | |
| Bioavailability | <5% with prolonged use |
| Protein binding | 94 to 97% |
| Metabolism | ? |
| Half life | 1.7 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Topical (applied as a nail lacquer) |
Ciclopirox (also called Loprox® and Penlac®) is a synthetic antifungal agent for topical dermatologic use.
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
| Antifungals (D01 and J02) edit | ||
|---|---|---|
| Antibiotics: | Griseofulvin, Hitachimycin, Natamycin, Nystatin | |
| Topical Azoles: | Clotrimazole, Econazole, Fluconazole, Ketoconazole, Miconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole | |
| Other topicals: | Ciclopirox, Ethylparaben, Flucytosine, Salicylic acid, Selenium sulfide, Terbinafine, Tolnaftate | |
| For systemic use: | Amphotericin B, Anidulafungin, Caspofungin, Griseofulvin, Itraconazole, Terbinafine, Voriconazole | |
| Other: | Posaconazole, Thiabendazole, Tea tree oil | |
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