Constitutive androstane receptor
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| nuclear receptor subfamily 1, group I, member 3
| |
| Identifiers | |
| Symbol(s) | NR1I3 |
| Entrez | 9970 |
| OMIM | 603881 |
| RefSeq | NM_005122 |
| UniProt | Q4U0F0 |
| Other data | |
| Locus | Chr. 1 q23.3 |
The constitutive androstane receptor (CAR) is a nuclear hormone receptor with activity similar to that seen in other steroid receptors such as estrogen or progesterone but more similar in form to PPAR, LXR and RXR. CAR functions somewhat differently from other steroid receptors and its activity is still being elucidated. It is known to act in concert with PXR to detoxify xenobiotics.
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