From Wikipedia, the free encyclopedia
Danaparoid sodium (Orgaran®) is an anticoagulant that works by inhibiting activated factor X (factor Xa). Danaparoid is considered a "low molecular weight heparin" but is chemically distinct from heparin and thus has little cross-reactivity in heparin-intolerant patients. It is used to prevent deep venous clots, particularly in situations with a high risk of clot formation, such as after hip surgery. It is also used as a heparinoid substitute in heparin-induced thrombocytopenia which may otherwise cause paradoxical thrombosis. This drug is no longer marketed in the United States.
[edit] Administration
IV
[edit] Side effects
- Bleeding problems
- Low platelets, due to a low level of structural similarity between danaparoid and heparin
- Asthma exacerbations, due to allergies to sulphites contained within the medicine
| Antithrombotics (thrombolytics, anticoagulants, and antiplatelet drugs) (B01) edit
|
| Vitamin K antagonists: |
Acenocoumarol,
Clorindione,
Dicumarol (Dicoumarol},
Diphenadione,
Ethyl biscoumacetate,
Phenprocoumon,
Phenindione,
Tioclomarol,
Warfarin
|
Heparin group (Platelet
aggregation inhibitors): |
Antithrombin III,
Bemiparin,
Dalteparin,
Danaparoid,
Enoxaparin,
Heparin,
Nadroparin,
Parnaparin,
Reviparin,
Sulodexide,
Tinzaparin
|
Other Platelet
aggregation inhibitors: |
Abciximab,
Acetylsalicylic acid (Aspirin),
Aloxiprin,
Beraprost,
Ditazole,
Carbasalate calcium,
Cloricromen,
Clopidogrel,
Dipyridamole,
Epoprostenol,
Eptifibatide,
Indobufen,
Iloprost,
Picotamide,
Prasugrel,
Ticlopidine,
Tirofiban,
Treprostinil,
Triflusal
|
| Enzymes: |
Alteplase,
Ancrod,
Anistreplase,
Brinase,
Drotrecogin alfa,
Fibrinolysin,
Protein C,
Reteplase,
Saruplase,
Streptokinase,
Tenecteplase,
Urokinase
|
| Direct thrombin inhibitors: |
Argatroban,
Bivalirudin,
Dabigatran,
Desirudin,
Hirudin,
Lepirudin,
Melagatran,
Ximelagatran
|
| Other antithrombotics: |
Dabigatran,
Defibrotide,
Dermatan sulfate,
Fondaparinux,
Rivaroxaban
|
| Non-medicinal: |
Citrate,
EDTA,
Oxalate
|
