Efferent arteriole
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| Efferent arteriole | |
|---|---|
| Scheme of renal tubule and its vascular supply. (Label "Efferent vessel" is visible in upper left.) | |
| Distribution of bloodvessels in cortex of kidney. | |
| Latin | arteriola glomerularis efferens |
| Gray's | subject #253 1221 |
| Dorlands/Elsevier | a_62/12156671 |
The Efferent arterioles are blood vessels that are part of the urinary system of many animals. The efferent arterioles form from a convergence of the capillaries of the glomerulus.
In the mammalian kidney they follow two markedly different courses, depending on the location of the glomeruli from which they arise.
In the mammalian kidney about 15% of glomeruli lie close to the boundary between the cortex and medulla and are known as "juxtamedullary" glomeruli. The rest are simply undifferentiated cortical glomeruli.
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[edit] In undifferentiated cortical glomeruli
The efferent arterioles of the undifferentiated cortical glomeruli are the simplest.
Promptly on leaving the glomerulus they break up into capillaries and become part of a rich plexus of vessels surrounding the cortical portions of the renal tubules.
Their chief function is to receive the resorbate from these tubules and return it to the general circulation.
[edit] In juxtamedullary glomeruli
The efferent arterioles of the juxtamedullary glomeruli are much different. They do break up, but they form bundles of vessels (arteriolae recti) that cross the outer zone of the medulla to perfuse the inner zone.
Vessels returning from the inner medulla (venulae recti) intersperse themselves in a highly regular fashion among the descending arteriolae recti to form a well organized rete mirabile.
This rete is responsible for the osmotic isolation of the inner medulla from the rest of the kidney and so permits the excretion of a hypertonic urine when circumstances require.
Interestingly, since the rete also isolates the inner medulla from gaseous exchange, any metabolism in this area is anaerobic, and red cells, which would serve no purpose there, are ordinarily shunted from the arteriolae recti by an unknown mechanism into the capillary plexus surrounding the tubules of the outer zone of the medulla.
Blood in this plexus and returning from the inner medulla finds its way to the renal vein and the general circulation by pathways similar to those providing drainage for the rest of the cortex.


