G cell
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In medicine, the G cell is a type of cell in the stomach that secrets gastrin.<ref>Diagram at gerd.com</ref> It works in conjunction with gastric chief cells and parietal cells.
G cells are found deep with the gastric glands of the stomach antrum, and occasionally in the pancreas.<ref>Medcyclopaedia at GE iv_1/g/G_cell</ref>
The vagus nerve innervates the G cells.
Gastrin-releasing peptide is released by the post-ganglionic fibers of the vagus nerve onto G cells during parasympathetic stimulation.
Gastrin-releasing peptide, as well as the presence of amino acids in the stomach, stimulate the release of gastrin from the G cells. Gastrin stimulates enterochromaffin cells to release histamine.
Gastrin also targets parietal cells.
The increase and histamine and the direct stimulation by gastrin, cause parietal cells to increase HCl secretion in the stomach.
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| Upper gastrointestinal tract
Mouth | Pharynx (nasopharynx, oropharynx, hypopharynx) | Esophagus | Crop | Stomach (rugae, gastric pits, cardia, pylorus) Lower gastrointestinal tract Small intestine (duodenum, jejunum, ileum) | Vermiform appendix Large intestine: Cecum | Colon (ascending colon, transverse colon, descending colon, sigmoid colon) | Rectum (Houston valve, rectal ampulla, pectinate line) | Anal canal (anal valves, anal sinuses, anal columns) Anus: Sphincter ani internus muscle | Sphincter ani externus muscle Enteric nervous system: Meissner's plexus | Auerbach's plexus Enteroendocrine cells: G cells | Enterochromaffin cells | Enterochromaffin-like cell GALT: Peyer's patches | M cells parietal cells | chief cells | goblet cells | Brunner's glands | Paneth cells | enterocytes intestinal villus/microvillus | crypts of Lieberkühn | circular folds | taenia coli | haustra | epiploic appendix |
