Genetic architecture
From Wikipedia, the free encyclopedia
Genetic architecture refers to the underlying genetic basis of a phenotypic trait. It encompasses both the number of genes and their importance in determining the phenotype (e.g., many genes of small effect vs. few genes of large effect).
| The development of phenotype
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| Key concepts: Genotype-phenotype distinction | Norms of reaction | Gene-environment interaction | Heritability | Quantitative genetics |
| Genetic architecture: Dominance relationship | Epistasis | Polygenic inheritance | Pleiotropy | Plasticity | Canalisation | Fitness landscape |
| Non-genetic influences: Epigenetic inheritance | Epigenetics | Maternal effect | Dual inheritance theory |
| Developmental architecture: Segmentation | Modularity |
| Evolution of genetic systems: Evolvability | Mutational robustness | Evolution of sex |
| Influential figures: C. H. Waddington | Richard Lewontin |
| Debates: Nature versus nurture |
| List of evolutionary biology topics |
