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Granulocyte

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Image:PBEosinophil.jpg
Eosinophil granulocyte
Image:PBBasophil.jpg
Basophil granulocyte

Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes.

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[edit] Classificiation

There are three types of granulocytes, distinguished by their appearance under Wright's stain:

Their names are derived from their staining characteristics; for example, the most abundant granulocyte is the neutrophil granulocyte, which has neutrally-staining cytoplasmic granules.

Other white blood cells which are not granulocytes ("agranulocytes") are mainly lymphocytes and monocytes.

[edit] Pathology

Granulocytopenia is an abnormally low concentration of granulocytes in the blood. This condition reduces the body's resistance to many infections. Closely-related terms include agranulocytosis and neutropenia.

A granuloma is a tumor containing granulocytes, and a "granulomatosis" is a necrotizing granuloma.

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Blood - Blood plasma
Pluripotential hemopoietic stem cells | Red blood cells (ReticulocyteNormoblast) | White blood cells
Lymphoid
T cells (CytotoxicHelperRegulatory T cellsNatural Killer T cells) | B cells (Plasma cells & Memory B cells) | Natural killer cells
Myeloid
Granulocytes (NeutrophilEosinophilBasophil) | Mast cell precursors | Monocytes (HistiocyteMacrophagesDendritic cellsLangerhans cells, MicrogliaKupffer cellsOsteoclasts) | Megakaryoblast | Megakaryocyte | Platelets
de:Granulozyt

es:Granulocito eo:Granulocito fr:Granulocyte it:Granulocita he:גרנולוציט nl:Granulocyt pl:Granulocyt pt:Agranulócito ru:Гранулоциты sk:Granulocyt fi:Granulosyytti sv:Granulocyt tr:Granülosit

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