Hypophosphatemia
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| Phosphate group chemical structure | |
| ICD-10 | E83.3 |
| ICD-9 | 275.3 |
| DiseasesDB | 6503 |
| MedlinePlus | 000307 |
| eMedicine | med/1135 |
Hypophosphatemia is an electrolyte disturbance in which there is an abnormally depleted level of phosphate in the blood. This can be caused when malnourished patients are fed a large amount of carbohydrates which have a high phosphorus demand (refeeding syndrome).
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[edit] Causes
- alcohol abuse
- burns
- hepatic failure
- malabsorption
- metabolic acidosis
- osteomalacia
- respiratory alkalosis
[edit] Pathophysiology
Hypophosphatemia is caused by the following three mechanisms:
- Inadequate intake (uncommon, seen in refeeding after long-term low phosphate intake)
- Increased excretion (e.g. in hyperparathyroidism)
- Shift from extracellular to intracellular space (seen in treatment of diabetic ketoacidosis, refeeding, short-term increases in cellular demand (eg, hungry bones syndrome) and acute respiratory alkalosis)
[edit] See also
[edit] External links
