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Ibotenic acid

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Ibotenic acid
Chemical nameα-Amino-2,3-dihydro-2-oxo-5-oxazoleacetic acid
Chemical formulaC5H6N2O4
Molecular mass158.11 g/mol
Melting Point151-152° (anhydrous); 144-146° (monohydrate)
SolubilitySoluble in methanol
CAS number2552-55-8
SMILES NC(C(=O) O) c1cc(=O) [nH]o1
chemical structure of ibotenic acid

Ibotenic acid is a toxic, possibly psychoactive compound present in Amanita muscaria and Amanita pantherina.

[edit] Effects

When ingested, a small amount of ibotenic acid is decarboxylated into muscimol, causing an initial drowsiness, followed by a four hour long excited state. The excited state consists of delirium, muscle spasms, and hallucinations.

[edit] History

The Ibotenic acid/muscimol found in Amanita muscaria and Amanita pantherina was used by Siberian shamans as a sacrament. Muscimol is excreted in the urine, and there are stories of shamans "reusing" urine for intoxication purposes. Ibotenic acid is also used in surgery. When injected introcranially, ibotenic acid causes exitotoxic axon sparing lesions of the brain.

See also: muscimol, muscazone

[edit] External links

hu:Iboténsav ja:イボテン酸 no:Ibotensyre pl:Kwas ibotenowy fi:Iboteenihappo tr:İbotenik asit


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