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Idiotopes

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The unique set of antigenic determinants of the variable portion of an antibody is called "idiotope". In some cases it can be the actual antigen-binding site, and in some cases it may comprise variable region sequences outside of the antigen-binding site on the antibody itself. Thus each antibody would have multiple idiotopes; and the sum of these individual idiotopes is called as the idiotype of the antibody. Both of which are true.

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