Interleukin 28
From Wikipedia, the free encyclopedia
| Interleukin 28A
| |
| Identifiers | |
| Symbol(s) | IL28A , IFNL2 |
| Entrez | 282616 |
| OMIM | 607401 |
| RefSeq | NM_172138 |
| UniProt | Q8IZJ0 |
| Other data | |
| Locus | Chr. 19 q13.13 |
| Interleukin 28B
| |
| Identifiers | |
| Symbol(s) | IL28B , IFNL3 |
| Entrez | 282617 |
| OMIM | 607402 |
| RefSeq | NM_172139 |
| UniProt | Q8IZI9 |
| Other data | |
| Locus | Chr. 19 q13.13 |
Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, with a role in immune defense against viruses.<ref>D. Kempuraj et al., Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities. International Journal of Immunopathology and Pharmacology, 2004, Volume 17, pages 103-106.</ref> IL-28A and IL-28B are highly related in amino acid sequence to IL-29, and belong to the type I interferon family of cytokines. IL-28 genes can be found near IL-29 on chromosome 19 in humans.
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