Isosorbide dinitrate
From Wikipedia, the free encyclopedia
| |
| Isosorbide dinitrate
| |
| Systematic (IUPAC) name | |
| 4,8-dinitrooxy-2,6-dioxabicyclo[3.3.0]octane | |
| Identifiers | |
| CAS number | 87-33-2 |
| ATC code | C01DA08 |
| PubChem | 3780 |
| DrugBank | APRD00455 |
| Chemical data | |
| Formula | C6H8N2O8 |
| Mol. weight | 236.136 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 10–90%, average 25% |
| Metabolism | Hepatic |
| Half life | 1 hour |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status |
℞ Prescription only |
| Routes | Oral |
Isosorbide dinitrate is a nitrate used pharmacologically as a vasodilator, e.g. in angina pectoris but also for anal fissure, a condition which is known to involve decreased blood supply leading to poor healing.
Isosorbide dinitrate is sold under the brand names Isordil® and Sorbitrate®. It is also a component of BiDil.
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
| Nitrates (C01D) edit | ||
|---|---|---|
|
Glyceryl trinitrate, Isosorbide dinitrate, Isosorbide mononitrate, Molsidomine, Pentaerythritol tetranitrate | ||
