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Crypts of Lieberkühn

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Crypts of Lieberkühn
An intestinal gland from the human intestine.
Latin glandulae intestinales
Gray's subject #248 1174
Dorlands/Elsevier g_06/12392417

The crypts of Lieberkühn (or intestinal glands) are glands found in the epithelial lining of the small intestine and colon. Named after the 18th-century German anatomist Johann Nathanael Lieberkühn, the crypts secrete various enzymes, including sucrase and maltase. Loss of proliferation control in the crypts is thought to lead to colorectal cancer.

In duodenum, Crypts of Lieberkühn are present and usually longer and straighter than those of the small intestine.

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Gastrointestinal tract

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Upper gastrointestinal tract

Mouth | Pharynx (nasopharynx, oropharynx, hypopharynx) | Esophagus | Crop | Stomach (rugae, gastric pits, cardia, pylorus)

Lower gastrointestinal tract

Small intestine (duodenum, jejunum, ileum) | Vermiform appendix

Large intestine: Cecum | Colon (ascending colon, transverse colon, descending colon, sigmoid colon) | Rectum (Houston valve, rectal ampulla, pectinate line) | Anal canal (anal valves, anal sinuses, anal columns)

Anus: Sphincter ani internus muscle | Sphincter ani externus muscle

Enteric nervous system: Meissner's plexus | Auerbach's plexus

Enteroendocrine cells: G cells | Enterochromaffin cells | Enterochromaffin-like cell

GALT: Peyer's patches | M cells

parietal cells | chief cells | goblet cells | Brunner's glands | Paneth cells | enterocytes

intestinal villus/microvillus | crypts of Lieberkühn | circular folds | taenia coli | haustra | epiploic appendix

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