List of sequenced eukaryotic genomes
From Wikipedia, the free encyclopedia
This list of sequenced eukaryotic genomes contains all the eukaryotes known to have publicly available complete genome sequences that have been assembled, annotated and published; draft genomes are not included.
DNA was first sequenced in 1977, the genome of Haemophilus influenzae was the first genome of a free-living organism to be sequenced. In 1996 Saccharomyces cerevisiae was the first eukaryote genome sequence to be released and in 1998 the first genome sequence for a multicellular eukaryote, Caenorhabditis elegans, was released.
| Organism | Type | Relevance | Genome size | Number of genes predicted | Organization | Year of completion |
|---|---|---|---|---|---|---|
| Anopheles gambiae Strain: PEST | Mosquito | Vector of malaria | 27.8 Mb | 13,683<ref name = "Holt">Holt RA, et al. The genome sequence of the malaria mosquito Anopheles gambiae. Science. 2002 Oct 4;298(5591):129-49. PMID 12364791</ref> | Celera Genomics and Genoscope | 2002<ref name = "Holt"/> |
| Apis mellifera | Honey bee | 10,157<ref name = "The Honeybee Genome Sequencing Consortium">Honeybee Genome Sequencing Consortium. Insights into social insects from the genome of the honeybee Apis mellifera. Nature. 2006 Oct 26;443(7114):931-49. PMID 17073008</ref> | The Honeybee Genome Sequencing Consortium | 2006<ref name = "The Honeybee Genome Sequencing Consortium"/> | ||
| Arabidopsis thaliana Ecotype:Columbia | Wild mustard | Model plant | 120 Mb | 25,498<ref name = "Arab">The Arabidopsis Genome Initiative. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature. 2000 Dec 14;408(6814):796-815. PMID 11130711</ref> | Arabidopsis Genome Initiative<ref>Arabidopsis Genome Initiative</ref> | 2000<ref name = "Arab"/> |
| Ashbya gossypii Strain:ATCC 10895 | Fungus | Plant pathogen | 9.2 Mb | 4,718<ref name= "Dietrich">Dietrich FS. et al. The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome. Science 2004 Apr 9;304(5668):304-7. PMID 15001715</ref> | SyngentaAG and University of Basel | 2004<ref name= "Dietrich"/> |
| Aspergillus fumigatus Strain:Af293 | Fungus | Human pathogen | 29.4 Mb | 9,926<ref name = "Nierman">Nierman WC, et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature. 2006 Jan 26;439(7075):502. PMID 16372009</ref> | Sanger Institute, University of Manchester, TIGR, Institut Pasteur, Nagasaki University, University of Salamanca and OpGen | 2005<ref name = "Nierman"/> |
| Aspergillus nidulans Strain:FGSC A4 | Fungus | Human pathogen, model organism | 30 Mb | 9,500<ref name = "Galagan">Galagan, JE, et al. Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature 2005 Dec 22;438(7071):1105-15. PMID 16372000</ref> | 2005<ref name = "Galagan"/> | |
| Aspergillus oryzae Strain:RIB40 | Fungus | Used to ferment soy | 37 Mb | 12,074<ref name = "Machidam"> Machidam M, et al. Genome sequencing and analysis of Aspergillus oryzae. Nature 2005 Dec 22;438(7071):1157-61. PMID 16372010 </ref> | National Institute of Technology and Evaluation | 2005<ref name = "Machidam"/> |
| Bombyx mori Strain:p50T | Moth (domestic silk worm) | Silk production | 530 Mb | University of Tokyo and National Institute of Agrobiological Sciences | 2004<ref>Mita K, et al. The genome sequence of silkworm, Bombyx mori. DNA Res. 2004 Feb 29;11(1):27-35. PMID 15141943</ref> | |
| Caenorhabditis briggsae | Nematode worm | For comparison with C. elegans | 104 Mb | 19,500<ref name ="Stein">Stein LD, et al. The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol. 2003 Nov;1(2):166-192. PMID 14624247</ref> | Washington University, Sanger Institute and Cold Spring Harbor Laboratory | 2003<ref name ="Stein"/> |
| Caenorhabditis elegans Strain:Bristol N2 | Nematode worm | Model animal | 97 Mb | 19,000<ref name = "C.elegans">C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science. 1998 Dec 11;282(5396):2012-8. PMID 9851916</ref> | Washington University and the Sanger Institute | 1998<ref name = "C.elegans"/> |
| Candida glabrata Strain:CBS138 | Fungus | Human pathogen | 12.3 Mb | 5,283<ref name = "Dujon">Dujon B, et al. Genome evolution in yeasts. Nature. 2004 Jul 1;430(6995):35-44. PMID 15229592</ref> | Génolevures Consortium <ref>About Génolevures</ref> | 2004<ref name = "Dujon"/> |
| Canis familiaris | Dog | 2.4 Gb | 19,300<ref name = "Dog">Lindblad-Toh K. et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 2005 Dec 8;438(7069):803-19. PMID 16341006</ref> | Broad Institute and Agencourt Bioscience | 2005<ref name = "Dog"/> | |
| Ciona intestinalis | Tunicate | Simple cordate | 116.7 Mb | 16,000<ref name ="Dehal">Dehal P, et al. The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science. 2002 Dec 13;298(5601):2157-67. PMID 12481130</ref> | Joint Genome Institute | 2003<ref name = "Dehal"/> |
| Cryptococcus (Filobasidiella) neoformans JEC21 | Fungus | Human pathogen | 20 Mb | 6,500<ref name ="Loftus">Loftus BJ, et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science. 2005 Feb 25;307(5713):1321-4. PMID 15653466</ref> | TIGR and Stanford University | 2005<ref name ="Loftus"/> |
| Cryptosporidium hominis Strain:TU502 | Parasitic protozoan | Human pathogen | 10.4 Mb | 3,994<ref name = "Xu">Xu P, et al. The genome of Cryptosporidium hominis. Nature. 2004 Oct 28;431(7012):1107-12. PMID 15510150</ref> | Virginia Commonwealth University | 2004<ref name = "Xu"/> |
| Cryptosporidium parvum C- or genotype 2 isolate | Parasitic protozoan | Human pathogen | 16.5 Mb | 3,807<ref name ="parvum">Abrahamsen MS, et al. Complete genome sequence of the apicomplexan, Cryptosporidium parvum. Science. 2004 Apr 16;304(5669):441-5. PMID 15044751</ref> | UCSF and University of Minnesota | 2004<ref name ="parvum"/> |
| Cyanidioschyzon merolae Strain:10D | Red alga | Simple eukaryote | 16.5 Mb | 5,331<ref name ="Matsuzaki">Matsuzaki M, et al. Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D. Nature. 2004 Apr 8;428(6983):653-7. PMID 15071595</ref> | University of Tokyo, Rikkyo University, Saitama University and Kumamoto University | 2004<ref name ="Matsuzaki"/> |
| Debaryomyces hansenii Strain:CBS767 | Yeast | Cheese ripening | 12.2 Mb | 6,906<ref name = "Dujon"/> | Génolevures Consortium | 2004<ref name = "Dujon"/> |
| Dictyostelium discoideum Strain:AX4 | Slime mold | Model organism | 34 Mb | 12,500<ref name = "Eichinger,L.">Eichinger L, et al. The genome of the social amoeba Dictyostelium discoideum. Nature. 2005 May 5;435(7038):43-57. PMID 15875012</ref> | Consortium from University of Cologne, Baylor College of Medicine and the Sanger Centre | 2005<ref name = "Eichinger,L."/> |
| Drosophila melanogaster | Fruit fly | Model animal | 165 Mb | 13,600<ref name = "Adams">Adams MD, et al. The Genome Sequence of Drosophila melanogaster. Science. 2000 Mar 24;287(5461):2185-95. PMID 10731132</ref> | Celera, UC Berkeley, Baylor College of Medicine, European DGP | 2000<ref name = "Adams"/> |
| Encephalitozoon cuniculi | Microsporidium | Human pathogen | 2.9 Mb | 1,997<ref name = "Katinka">Katinka MD, et al. Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi. Nature. Nov 22;414(6862):450-3. PMID 11719806</ref> | Genoscope and Université Blaise Pascal | 2001<ref name = "Katinka"/> |
| Entamoeba histolytica HM1:IMSS | Parasitic protozoan | Human pathogen (amoebic dysentery) | 23.8 Mb | 9,938<ref name ="Loftus B">Loftus B, et al. The genome of the protist parasite Entamoeba histolytica. Nature. 2005 Feb 24;433(7028):865-8. PMID 15729342</ref> | TIGR, Sanger Institute and the London School of Hygiene and Tropical Medicine | 2005<ref name = "Loftus B"/> |
| Gallus gallus | Chicken | 1 Gb | 20-23,000<ref name = "Chicken">International Chicken Genome Sequencing Consortium. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 2004 Dec 9;432(7018):695-716. PMID 15592404</ref> | International Chicken Genome Sequencing Consortium | 2004<ref name = "Chicken"/> | |
| Guillardia theta | Alga | Model organism | 551 Kb | 464<ref name ="Douglas">Douglas S. et al. The highly reduced genome of an enslaved algal nucleus. Nature. 2001 Apr 26;410(6832):1091-6. PMID 11323671</ref> | Canadian Institute of Advanced Research, Philipps-University Marburg and the University of British Columbia | 2001<ref name ="Douglas"/> |
| Homo sapiens | Human | 3.2 Gb | 25,000<ref>International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature. 2004 Oct 21;431(7011):931-45. PMID 15496913</ref> | Human Genome Project Consortium and Celera Genomics | Drafts 2001;<ref> The International Human Genome Mapping Consortium. A physical map of the human genome. Nature 2001 Feb 15;409(6822):934-41. PMID 11237014</ref><ref>The Celera Genomics Sequencing Team. The sequence of the human genome. Science. 2001 Feb 16;291(5507):1304-51. PMID 11181995</ref> all chromosomes complete 2006<ref>Gregory SG, et al. The DNA sequence and biological annotation of human chromosome 1. Nature. 2006 May 18;441(7091):315-21. PMID 16710414</ref> | |
| Kluyveromyces lactis Strain:CLIB210 | Yeast | 10-12 Mb | 5,329<ref name = "Dujon"/> | Génolevures Consortium | 2004<ref name = "Dujon"/> | |
| Leishmania major Strain:Friedlin | Parasitic protozoan | Human pathogen | 32.8 Mb | 8,272<ref name = "Ivens">Ivens AC, et al. The genome of the kinetoplastid parasite, Leishmania major. Science 2005 Jul 15;309(5733):436-42. PMID 16020728</ref> | Sanger Institute | 2005<ref name = "Ivens"/> |
| Magnaporthe grisea | Fungus | Plant pathogen | 37.8 Mb | 11,109<ref name = "Dean">Dean RA et al. The genome sequence of the rice blast fungus Magnaporthe grisea. Nature. 2005 Apr 21;434(7036):980-6. PMID 15846337</ref> | 2005<ref name = "Dean"/> | |
| Mus musculus | Mouse | Model mammal | 2.5 Gb | 24,174<ref name = "Waterston RH">Waterston RH, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 2002 Dec 5;420(6915):520-62. PMID 12466850</ref> | International Collaboration for the Mouse Genome Sequencing<ref>International Collaboration for the Mouse Genome Sequencing</ref> | 2002<ref name = "Waterston RH"/> |
| Neurospora crassa | Fungus | 40 Mb | 10,082<ref name ="Galagan">Galagan JE, et al. The genome sequence of the filamentous fungus Neurospora crassa. Nature. 2003 Apr 24;422(6934):859-68. PMID 12712197</ref> | Broad Institute, Oregon Health and Sceince University, University of Kentucky, and the University of Kansas | 2003<ref name ="Galagan"/> | |
| Oryza sativa ssp indica | Rice | Crop and model organism | 420 Mb | 32-50,000<ref name ="Goff">Goff SA, et al. A draft sequence of the rice genome (Oryza sativa L. ssp. japonica). Science. 2002 Apr 5;296(5565):92-100. PMID 11935018</ref> | Beijing Genomics Institute, Zhejiang University and the Chinese Academy of Sciences | 2002<ref name ="Goff"/> |
| Oryza sativa ssp japonica | Rice | Crop and model organism | 466 Mb | 46,022-55,615<ref name = "Yu">Yu J, et al. A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science. 2002 Apr 5;296(5565):79-92. PMID 11935017</ref> | Syngenta and Myriad Genetics | 2002<ref name = "Yu"> |
| Ostreococcus tauri | Alga | Simple eukaryote | 12.6 Mb | Laboratoire Arago | 2006<ref>Derelle E, et al. Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11647-52. PMID 16868079</ref> | |
| Pan troglodytes | Chimpanzee | Closest human relative | 3.1 Gb | Chimpanzee Sequencing and Analysis Consortium | 2005<ref>Chimpanzee Sequencing and Analysis Consortium. Initial sequence of the chimpanzee genome and comparison with the human genome. Nature. 2005 Sep 1;437(7055):69-87. PMID 16136131</ref> | |
| Paramecium tetraurelia | Ciliate | Model organism | 100 Mb | 30,000<ref name = "Zagulski">Zagulski M, et al. High coding density on the largest Paramecium tetraurelia somatic chromosome. Curr Biol. 2004 Aug 10;14(15):1397-404. PMID 15296759</ref> | 2004<ref name = "Zagulski"/> | |
| Plasmodium falciparum Clone:3D7 | Parasitic protozoan | Human pathogen (malaria) | 22.9 Mb | 5,268<ref name = "Gardener">Gardener MJ, et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 2002 Oct 3;419(6906):498-511. PMID 12368864</ref> | Malaria Genome Project Consortium | 2002<ref name = "Gardener"/> |
| Plasmodium yoelii yoelii Stain:17XNL | Parasitic protozoan | Rodent pathogen (malaria) | 23.1 Mb | 5,878<ref name = "Carlton">Carlton JM. et al. Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii. Nature. 2002 Oct 3;419(6906):512-9. PMID 12368865</ref> | TIGR and NMRC | 2002<ref name = "Carlton"/> |
| Populus trichocarpa | Tree (Balsam poplar) | 550 Mb | 45,555<ref name = "Tuskan">Tuskan GA, et al. The Genome of Black Cottonwood, Populus trichocarpa (Torr. & Gray). Science. 2006 Sep 15;313(5793):1596-604. PMID 16973872</ref> | 2006<ref name = Tuskan/> | ||
| Rattus norvegicus BN/SsNHsdMCW | Rat | Model mammal | 6.8 Gb | 21,166<ref name ="Gibbs">Gibbs RA, et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 2004 Apr 1;428(6982):493-521. PMID 15057822</ref> | 2004<ref name ="Gibbs"/> | |
| Saccharomyces cerevisiae Strain:S288C | Yeast (baker's yeast) | Model eukaryote | 12.1 Mb | 6,294<ref name = "Goffeau">Goffeau A, et al. Life with 6000 genes. Science. 1996 Oct 25;274(5287):546, 563-7. PMID 8849441</ref> | International Collaboration for the Yeast Genome Sequencing<ref>International Collaboration for the Yeast Genome Sequencing</ref> | 1996<ref name = "Goffeau"/> |
| Schizosaccharomyces pombe Strain:972h | Yeast | Model eukaryote | 14 Mb | 4,824<ref name = "Wood">Wood V, et al. The genome sequence of Schizosaccharomyces pombe. Nature. 2002 Feb 21;415(6874):871-80. PMID 11859360</ref> | Sanger Institute and Cold Spring Harbor Laboratory | 2002<ref name = "Wood"/> |
| Strongylocentrotus purpuratus | Sea urchin | Model eukaryote | 814 Mb | 23,300<ref name = "SUGC"> Sodergren E, et al. The Genome of the Sea Urchin Strongylocentrotus purpuratus. Science. 2006 Nov 10;314(5801):941-952. PMID 17095691</ref> | Sea Urchin Genome Sequencing Consortium | 2006<ref name = "SUGC"/> |
| Takifugu rubripes | Puffer fish | Vertebrate with small genome | 390 Mb | 22-29,000<ref>International Fugu Genome Consortium. Forth Genome Assembly</ref> | International Fugu Genome Consortium<ref>International Fugu Genome Consortium</ref> | 2002<ref>Aparicio S, et al. Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science. 2002 Aug 23;297(5585):1301-10. PMID 12142439</ref> |
| Tetraodon nigroviridis | Puffer fish | Vertebrate with small genome | 385 Mb | Genoscope and the Broad Institute | 2004<ref>Jaillon O, et al. Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature. 2004 Oct 21;431(7011):946-57. PMID 15496914</ref> | |
| Thalassiosira pseudonana Strain:CCMP 1335 | Diatom | 2.5 Mb | 11,242<ref name = "Armbrust EV">Armbrust EV, et al. The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism. Science. 2004 Oct 1;306(5693):79-86. PMID 15459382</ref> | Joint Genome Institute and the University of Washington | 2004<ref name = "Armbrust EV"/> | |
| Theileria parva Strain:Muguga | Parasitic protozoan | Cattle pathogen (African east coast fever) | 8.3 Mb | 4,035<ref name ="Gardner MJ">Gardner MJ, et al. Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes. Science. 2005 Jul 1;309(5731):134-7. PMID 15994558</ref> | TIGR and the International Livestock Research Institute | 2005<ref name ="Gardner MJ"/> |
| Trypanosoma brucei Strain:TREU927/4 GUTat10.1 | Parasitic protozoan | Human pathogen ("Sleeping sickness") | 26 Mb | 9,068 <ref name = "Berriman M">Berriman, M. et al. 2005. The genome of the African trypanosome Trypanosoma brucei. Science 309:416-22</ref> | Sanger Institute and TIGR | 2005<ref name = "Berriman M"/> |
| Trypanosoma cruzi Strain:CL Brener TC3 | Parasitic protozoan | Human pathogen (Chagas disease) | 34 Mb | 22,570<ref name = "El-Sayed NM">El-Sayed, N.M. et al. 2005. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 309:409-15</ref> | TIGR, Seattle Biomedical Research Institute and Uppsala University | 2005<ref name = "El-Sayed NM"/> |
| Yarrowia lipolytica Strain:CLIB99 | Yeast | Industrial uses | 20 Mb | 6,703<ref name = "Dujon"/> | Génolevures Consortium | 2004<ref name = "Dujon"/> |
[edit] See also
[edit] References
<references/>
[edit] External links
- EMBL-EBL Eukaryotic Genomes
- UCSC Genome Browser
- International Sequencing Consortium - Large-scale Sequencing Project Database
- Ensembl Genome Browser (includes draft and low coverage genomes)
- Fungal Genome Initiative (includes draft genomes)
- GOLD:Genomes OnLine Database v 2.0

