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Malpighian layer (or Malpighi layer, named after Marcello Malpighi, also called germinative layer or basal cell layer; Latin: stratum Malpighii, stratum germinativum) is a thin 1,88 mm thick basal and the deepest layer of the epidermis composed of dividing stem cells and anchoring cells, and the prickle cell layer considered as one unit. Skin originates at the bottom of the layer and grows outward.

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• Malpighi layer of ox, sheep, goat and pig's foot