Neurokinin 1
From Wikipedia, the free encyclopedia
(Redirected from Neurokinin)
| tachykinin, precursor 1
| |
| Identifiers | |
| Symbol(s) | TAC1 TAC2, NKNA |
| Entrez | 6863 |
| OMIM | 162320 |
| RefSeq | NM_003182 |
| UniProt | P20366 |
| Other data | |
| Locus | Chr. 7 q21-q22 |
[edit] General information
Neurokinin 1 is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins. The protein is the product of the TACR1 gene. There are at least 2 other Neurokinin receptors, Neurokinin 2 and 3. These receptors have varying ligand affinities and activities.
This protein is considered an attractive drug target.
Neurokinin 1 antagonists may have a role as novel antiemetics.
[edit] See also
[edit] References
this section is inherently incomplete. There is a large body of research regarding this receptor
"The Mammalian Tachykinin Receptors", Maggi CA (1995), Gen Pharm, Vol. 26, Issue 5, pp. 911-944
 | This protein-related article is a stub. You can help Wikipedia by expanding it. |
