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Image:NisslHippo2.jpg Image:Gray626.png A Nissl body (or Nissl granule or tigroid body) is a large granular body found in nerve cells. It was named after Franz Nissl, German neurologist (1860-1919).

Nissl bodies can be demonstrated by selective staining, which was developed by Nissl and was an aniline stain used to label extranuclear RNA granules.

These granules are rough endoplasmic reticulum (with ribosomes) and are the site of protein synthesis.

Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (karyolysis).

[edit] See also

• Franz Nissl

[edit] External links

• MeSH Nissl+Bodies
• synd/2902 at Who Named It
• Histology at BU 04103loa - "Nervous Tissue and Neuromuscular Junction: spinal cord, cell bodies of anterior horn cells"
• Labeled photo at mun.ca (halfway down page)
• Tissues containing Nissl bodies at harvard.edu

de:Nissl-Färbung fr:coloration de Nissl

Nervous tissue - edit

Neurons (gray matter): soma, axon (axon hillock, axoplasm, axolemma, neurofibril/neurofilament), dendrite (Nissl body, dendritic spine) types (bipolar, pseudounipolar, multipolar, pyramidal, Purkinje, Renshaw, granule) Synapses: neuropil, boutons, synaptic vesicle, neuromuscular junction, electrical synapse Sensory receptors: Free nerve ending, Meissner's corpuscle, Merkel nerve ending, Muscle spindle, Pacinian corpuscle, Ruffini ending, Olfactory receptor neuron, Photoreceptor, Hair cell, Taste bud Glial cells: astrocyte, ependymal cells, microglia, radial glia Myelination (white matter): Schwann cell, oligodendrocyte, nodes of Ranvier, internode, Schmidt-Lanterman incisures, neurolemma closely related Connective tissue: epineurium, perineurium, endoneurium, nerve fascicle, meninges