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Nucleobase

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Nucleobase Nucleoside
Image:Adenine chemical structure.png
Adenine
Image:A chemical structure.png
Adenosine
A
Image:Guanine chemical structure.png
Guanine
Image:G chemical structure.png
Guanosine
G
Image:Thymine chemical structure.png
Thymine
Image:T chemical structure.png
Thymidine
T
Image:Uracil chemical structure.png
Uracil
Image:U chemical structure.png
Uridine
U
Image:Cytosine chemical structure.png
Cytosine
Image:C chemical structure.png
Cytidine
C
Image:Hypoxanthine chemical structure.svg
Hypoxanthine
Image:HX chemical structure.svg
Hypoxanthinosine
HX
Image:Xanthine chemical structure.svg
Xanthine
Image:X chemical structure.svg
Xanthinosine
X

Nucleobases are the parts of RNA and DNA that may be involved in pairing up (see also base pairs). These include cytosine, guanine, adenine, thymine (DNA), uracil (RNA) ans xanthine and hypoxanthine (mutated forms of guanine and, respectively, adenine). These are abbreviated as C, G, A, T, U, X and HX respectively. They are usually simply called bases in Genetics.

Uracil replaces thymine in RNA. These two bases are identical except that uracil lacks the 5' methyl group. Adenine and guanine belong to the double-ringed class of molecules called purines (abbreviated as R). Cytosine, thymine, and uracil are all pyrimidines (abbreviated as Y).

A base covalently bound to the 1' carbon of a ribose or deoxyribose is called a nucleoside, and a nucleoside with one or more phosphate groups attached at the 5' carbon is called a nucleotide.

Contents

[edit] Overall Information

Hypoxanthine and Xanthine are created through Mutagen presence, through De-amination (replacement of the Amine-Group with a Hydroxyl-Group). Hypoxanthine is produced from Adenine, Xanthin from Guanin and Uracil from Cytosin.

Because A, G, C and T appear in the DNA, these molecules are called DNA-bases; A, G, C and U are called respectively RNA-bases.

[edit] Structure

  • The "skeleton" of Adenine, Guanin, Hypoxanthine and Xanthine is Purine, hence the name Purin-bases.
  • The "skeleton" of Cytosin, Uracil and Thymin is Pyrimidine, hence Pyrimidine-bases.


[edit] See also

[edit] External links


Nucleic acids and oligonucleotides edit
Nucleobases: Adenine | Thymine | Uracil | Guanine | Cytosine | Purine | Pyrimidine
Nucleosides: Adenosine | Uridine | Guanosine | Cytidine | Deoxyadenosine | Thymidine | Deoxyguanosine | Deoxycytidine
Nucleotides: AMP | UMP | GMP | CMP | ADP | UDP | GDP | CDP | ATP | UTP | GTP | CTP | cAMP | cADPR | cGMP
Deoxynucleotides: dAMP | TMP | dGMP | dCMP | dADP | TDP | dGDP | dCDP | dATP | TTP | dGTP | dCTP
Ribonucleic acids: RNA | mRNA | tRNA | rRNA | ncRNA | sgRNA | shRNA | siRNA | snRNA | miRNA | snoRNA | LNA
Deoxyribonucleic acids: DNA | mtDNA | cDNA | plasmid | Cosmid | BAC | YAC | HAC
Analogues of nucleic acids: GNA | PNA | TNA| morpholino
←Amino acids Major families of biochemicals Carbohydrates→

cs:Nukleové báze de:Nukleinbasen eo:Nitrogena bazo es:base nitrogenada fr:Base azotée it:base azotata vi:nucleobase

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