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Nucleus ambiguus

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Brain: Nucleus ambiguus
Transverse section of medulla oblongata below the middle of the olive. ("Nucleus ambiguus" labeled at center right.)
Nuclei of origin of cranial motor nerves schematically represented; lateral view. (Nucleus ambiguus visible at bottom right.)
Gray's subject #187 779
NeuroNames hier-762
Dorlands/Elsevier n_11/12580164

The nucleus ambiguus (literally "ambiguous nucleus") is a region of histologically disparate cells located just dorsal (posterior) to the inferior olivary nucleus in the lateral portion of the upper (rostral) medulla. This nucleus gives rise to the efferent motor fibers of the vagus nerve (CN X) terminating in the laryngeal and pharyngeal muscles, as well as to the efferent motor fibers of the glossopharyngeal nerve (CN IX) terminating in the stylopharyngeus.

The muscles supplied by the vagus (included with this is the cranial part of the accessory nerve), such as levator veli palatini, are also necessary to swallow properly. The vagus also supplies the upper part of the esophagus, and other parts of the pharynx and larynx.

As well as motor functions, nucleus ambiguus also contains the preganglionic neurons for the heart.

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Rhombencephalon (hindbrain)

MYELENCEPHALON/MEDULLA: arcuate nucleus of medulla, solitary nucleus, hypoglossal nucleus, nucleus ambiguus, olivary body, inferior olivary nucleus, cuneate nucleus, accessory cuneate nucleus, gracile nucleus, inferior salivatory nucleus, raphe nuclei (obscurus, magnus, pallidus), area postrema, posterior nucleus of vagus nerve

METENCEPHALON/CEREBELLUM: cerebellar vermis, flocculus, arbor vitae

METENCEPHALON/PONS: pontine tegmentum, superior salivary nucleus, trapezoid body, pontine nuclei (superior olivary nucleus, trigeminal nerve nuclei, abducens nucleus, facial motor nucleus, cochlear nuclei, vestibular nuclei), locus ceruleus, paramedian pontine reticular formation, nucleus centralis superior

FOURTH VENTRICLE: obex, median aperture

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