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Image:Phenprocoumon.svg
Phenprocoumon
Systematic (IUPAC) name
2-hydroxy-3-(1-phenylpropyl)chromen-4-one
Identifiers
CAS number	435-97-2
ATC code	B01AA04
PubChem	9908
DrugBank	APRD00228
Chemical data
Formula	C18H16O3
Mol. weight	280.318 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	99%
Metabolism	hepatic to inactive metabolites
Half life	5 to 6 days
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Phenprocoumon is a anticoagulant, functioning as a Vitamin K antagonist. It is a derivative of coumarin and is also marketed under the brand name Marcoumar. It is a vitamin K antagonist that inhibits coagulation by blocking synthesis of coagulation factors II, VII, IX and X. It is used for the prophylaxis and treatment of thromboembolic disorders.

[edit] External links

• DDB 29943

de:Phenprocoumon

Antithrombotics (thrombolytics, anticoagulants, and antiplatelet drugs) (B01) edit
Vitamin K antagonists:	Acenocoumarol, Clorindione, Dicumarol (Dicoumarol}, Diphenadione, Ethyl biscoumacetate, Phenprocoumon, Phenindione, Tioclomarol, Warfarin
Heparin group (Platelet aggregation inhibitors):	Antithrombin III, Bemiparin, Dalteparin, Danaparoid, Enoxaparin, Heparin, Nadroparin, Parnaparin, Reviparin, Sulodexide, Tinzaparin
Other Platelet aggregation inhibitors:	Abciximab, Acetylsalicylic acid (Aspirin), Aloxiprin, Beraprost, Ditazole, Carbasalate calcium, Cloricromen, Clopidogrel, Dipyridamole, Epoprostenol, Eptifibatide, Indobufen, Iloprost, Picotamide, Prasugrel, Ticlopidine, Tirofiban, Treprostinil, Triflusal
Enzymes:	Alteplase, Ancrod, Anistreplase, Brinase, Drotrecogin alfa, Fibrinolysin, Protein C, Reteplase, Saruplase, Streptokinase, Tenecteplase, Urokinase
Direct thrombin inhibitors:	Argatroban, Bivalirudin, Dabigatran, Desirudin, Hirudin, Lepirudin, Melagatran, Ximelagatran
Other antithrombotics:	Dabigatran, Defibrotide, Dermatan sulfate, Fondaparinux, Rivaroxaban
Non-medicinal:	Citrate, EDTA, Oxalate