Prilocaine
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| Image:Prilocaine.png | |
| Prilocaine
| |
| Systematic (IUPAC) name | |
| N-(2-methylphenyl)-2-propylamino-propanamide | |
| Identifiers | |
| CAS number | 721-50-6 |
| ATC code | N01BB04 |
| PubChem | 4906 |
| DrugBank | APRD00180 |
| Chemical data | |
| Formula | C13H20N2O |
| Mol. weight | 220.311 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 98% |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Prilocaine (IPA: [ˈpraɪlokeɪn]) is a local anesthetic of the amino amide type. In its injectable form (Citanest®), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA). As it has low cardiac toxicity, it is commoly used for intravenous regional anaesthesia (IVRA).
In some patients, a metabolite of prilocaine may cause the unusual side-effect of methaemoglobinaemia.
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