Retinol binding protein
From Wikipedia, the free encyclopedia
Retinol Binding Proteins are a family of proteins with diverse functions. Retinol Binding Protein 4 (RBP4) has recently been described (Yang et al. 2005) as an adipokine that contributes to insulin resistance in the AG4KO mouse model. It is secreted by adipocytes, and can act as a signal to other cells, when there is a decrease in plasma glucose concentration (Herman & Kahn, 2006).
[edit] References
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- Herman, M.A and Kahn, B.B. (2006) Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. The Journal of Clincial Investigation. 116:1767-1775(see external link below)
- Yang, Q. et al. (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436:35-362
