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Image:Thiothixene.png
Thiothixene
Systematic (IUPAC) name
N,N-dimethyl-9- [3-(4-methylpiperazin-1-yl)propylidene]- thioxanthene-2-sulfonamide
Identifiers
CAS number	5591-45-7
ATC code	N05AF04
PubChem	5454
DrugBank	none
Chemical data
Formula	C23H29N3O2S2
Mol. weight	443.627
Pharmacokinetic data
Bioavailability	?
Metabolism	Hepatic
Half life	10-20 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	?
Routes	oral, IM

Thiothixene (sold as Navane®) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl- 9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.

Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as olanzapine.

Antipsychotics (N05A) edit
Phenothiazine typical antipsychotics:	Chlorpromazine, Fluphenazine, Mesoridazine, Perphenazine, Prochlorperazine, Promazine, Thioridazine, Trifluoperazine
Other typical antipsychotics:	Chlorprothixene, Droperidol, Flupentixol, Haloperidol, Loxapine, Molindone, Pimozide, Sulforidazine, Thiothixene
Atypical antipsychotics:	Amisulpride, Aripiprazole, Clozapine, Olanzapine, Quetiapine, Risperidone/Paliperidone, Sertindole, Sulpiride, Ziprasidone, Zotepine

sv:Tiotixen

ja:チオチキセン