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Toxic multinodular goitre

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Toxic multinodular goitre
Classifications and external resources
ICD-10 E05.2
ICD-9 242.3
DiseasesDB 13184
MedlinePlus 000317
eMedicine med/920 

Toxic multinodular goitre is also know as Toxic nodular goitre, or Toxic nodular struma, or Plummer's disease)

It is a form of hyperthyroidism - where there is excess production of thyroid hormones.

Symptoms of toxic multinodular goitre are similar to that of hyperthyroidism, including:

  • heat intolerance
  • hyperkinesis
  • tremor
  • irritability
  • weight loss
  • increased appetite
  • Goitre (swelling of the thyroid gland)
  • tachycardia (high heart rate - above 180 bpm at rest)

It is the second most common cause of hyperthyroidism after Grave's disease.

The type which is called Plummer's disease is named after an American physician Henry Stanley Plummer.


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