Tris
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| Tris | |
|---|---|
| Image:Tris structure.png | |
| General | |
| Systematic name | 2-amino-2-(hydroxymethyl)propane-1,3-diol |
| Other names | TRIS, Tris, Tris base, Tris buffer, Trizma(TM), Trisamine, THAM, Tromethamine, Trometamol, Tromethane,.. |
| Molecular formula | C4H11NO3 |
| SMILES | C(C(CO)(CO)N)O |
| Molar mass | 121.135 g/mol |
| Appearance | white crystalline powder |
| CAS number | [77-86-1] [1] |
| Properties | |
| Density and phase | ? g/l, solid (25°C) |
| Solubility in water | 67? g/100 ml (20°C) |
| Melting point | >170°C (443 K) |
| Boiling point | 219°C (492 K) |
| Acidity (pKa) | 8.3 |
| Hazards | |
| MSDS | External MSDS |
| Main hazards | Irritant. |
| NFPA 704 | |
| Flash point | Non-flammable. |
| R/S statement | R: R36, R37, R38. S: S26, S36. |
| RTECS number | TY2900000 |
| Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references | |
- This article is about a chemical. For the baseball player, see Tris Speaker.
- For other articles see Tris (disambiguation).
Tris is an abbreviation of the trivial name (trishydroxymethylaminomethane) for 2-amino-2-hydroxymethyl-1,3-propanediol. It is widely used as a buffering agent in biochemistry, with an effective pH range between 6.5 and 9.7. Tris has labile protons with a pKa of 8.30 (at 20 °C; this declines approximately 0.03 units per degree Celsius rise in temperature).
Tris is often used when working with nucleic acids.
[edit] Usage
Tris is used as an intermediate for the preparation of surface active agents, vulcanization accelerators, and pharmaceuticals, and used as a titrimetric standard.
[edit] External links
Categories: Alcohols | Amines | Buffers
