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Vasa recta

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Artery: Vasa recta
A nephron, the vasa recta is labelled arteria recta
Latin arteriolae rectae renis
Gray's subject #253 1224
Source Arcuate arteries of the kidney
Branches Straight venules of kidney, Arcuate vein
Dorlands/Elsevier a_62/12156708
Vasa rectas are also straight arteries coming off from arcades in the mesentery of the jejunum and ileum, and heading toward the intestines. Arcaded is an anatomosis of the jejunal and ilial arteries, branches of superior mesenteric artery.

In the blood supply of the kidney, the vasa recta renis (or straight arteries of kidney, or straight arterioles of kidney) form a series of straight capillaries (recta is from the Latin for "straight") that descend from the cortex into the medulla. These vessels branch off of the efferent arterioles of juxtamedullary nephrons (those nephrons closest to the medulla), enter the medulla, and surround the loop of Henle.

Each of the vasa recta has a hairpin turn in the medulla and carries blood at a very slow rate, two factors crucial in the maintenance of countercurrent exchange that prevent washout of the concentration gradients established in the renal medulla. The maintenance of this concentration gradient is one of the components responsible for the kidney's ability to produce concentrated urine.

[edit] Pathology

The slow blood flow in vasa recta makes them a likely place of thrombosis in hypercoagulable states, or erythrocyte sickling in sickle cell disease. Ischemia that results may lead to renal papillary necrosis.

[edit] External links

Urinary system - Kidney - edit
Renal capsule | Renal cortex | Renal medulla (Renal sinusRenal pyramids) | Renal calyx | Renal pelvis
Nephron - Renal corpuscle (GlomerulusBowman's capsule) → Proximal tubule → Loop of Henle → Distal convoluted tubule → Collecting ducts

Juxtaglomerular apparatus (Macula densaJuxtaglomerular cells, Extraglomerular mesangial cells)

Renal circulation - Renal artery → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Glomerulus → Efferent arterioles → Vasa recta → Arcuate veinRenal vein

Renal physiology
Filtration - Ultrafiltration | Countercurrent exchange

Hormones effecting filtration - Antidiuretic hormone (ADH) | Aldosterone | Atrial natriuretic peptide

Endocrine - Renin | Erythropoietin (EPO) | Calcitriol (Active vitamin D) | Prostaglandins

Assessing Renal function / Measures of dialysis
Glomerular filtration rate | Creatinine clearance | Renal clearance ratio | Urea reduction ratio | Kt/V | Standardized Kt/V | Hemodialysis product
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